01895nam a22002297a 450000500170000000800410001702000180005804000070007604100080008308200240009110000300011524500510014525000120019626000290020830000280023736500640026552011110032965000400144094200120148099900190149295201540151120240316114125.0240316b           ||||| |||| 00| 0 eng d  a9783030111410  cAL  aeng  223a574.19245bBUXF  aEngelbert Buxbaum9154870  aFundamentals of protein structure and function  a2nd ed.  aNew YorkbSpringerc2019  axvi,521p.bHBc24x15cm.  2Generala7743b₹2396.00c₹d₹2995.00e20%f15-02-2024  aThis book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance.  2BiochemistryaLife Sciences9154871  2ddccBK  c230454d230454  00102ddc40708ACaSACPGbSACPGd2024-03-01eBiblios Book Pointg2396.00l0o574.19245 BUXFpPG024669r2024-03-16 00:00:00v2995.00w2024-03-16yBK